We made a switch when our family was at WDW in October. We went from the POF to the Poly. We ended up wanting to add a few days onto our Land and Sea package, and Poly was booked.
We had an amazing vacation, but the switch is the one thing that dampened it. You have to set aside time to pack and unpack, and take time to check in at your new location. Although Disney Cast Members were all great during check in the process still takes a bit of time, and heaven for bid there is a line at the check in counter!
My advice would be to go with the hotel you would like to spend the most time at, and you find is most centrally located to the parks you want to see. The AKL is quite removed from everything.