I have driven from San Fran to Disneyland and from Yosemite to Disneyland. It’s a long six hours and make sure the last two hours are between the hours of 12:00 and 2:00am. We have gotten stuck in LA traffic (two hours through downtown) during rush hour and evening hours. A.M. is best.
I have also driven from San Simeon to Anaheim which was quite a days drive (with the tour of the castle and the drive back.) Whew!
Bring the DVD player and the GPS.
It worth the distance and time for the average Disney addict.
Also, avoid all highways to the beaches on Friday evenings. You can see your gas gage move but traffic doesn’t.